X-ray diffraction to determine the thickness of raft and nonraft bilayers.

Journal Article (Journal Article)

Low-angle X-ray diffraction is a powerful method to analyze the structure of membrane bilayers. Specifically, the technique can be used to determine accurately the thickness of fully hydrated bilayers. Herein details are presented showing how this technique can measure the difference in thickness of bilayers in detergent-resistant membranes and detergent-soluble membranes extracted from model systems known to contain both raft and nonraft domains. The observed thickness difference may be critical in the sorting of transmembrane proteins between raft and nonraft bilayers.

Full Text

Duke Authors

Cited Authors

  • McIntosh, TJ

Published Date

  • 2007

Published In

Volume / Issue

  • 398 /

Start / End Page

  • 221 - 230

PubMed ID

  • 18214383

International Standard Serial Number (ISSN)

  • 1064-3745

Digital Object Identifier (DOI)

  • 10.1007/978-1-59745-513-8_15


  • eng

Conference Location

  • United States