Non-viral charge reversal vectors for pDNA delivery.

Published

Journal Article

A synthetic vector that transform from a cationic to an anionic lipid intracellularly is described. This charge-reversal lipid was synthesized and characterized, including the supramolecular complex it forms with DNA. Enhanced gene transfection was observed using this synthetic vector compared to current cationic lipids.

Full Text

Duke Authors

Cited Authors

  • Prata, CAH; Li, Y; Luo, D; McIntosh, TJ; Grinstaff, MW

Published Date

  • 2006

Published In

Volume / Issue

  • 1 /

Start / End Page

  • 4347 - 4349

PubMed ID

  • 17946624

Pubmed Central ID

  • 17946624

International Standard Serial Number (ISSN)

  • 1557-170X

Digital Object Identifier (DOI)

  • 10.1109/IEMBS.2006.260181

Language

  • eng

Conference Location

  • United States