Fatal granulomatous Acanthamoeba encephalitis mimicking a stroke, diagnosed by correlation of results of sequential magnetic resonance imaging, biopsy, in vitro culture, immunofluorescence analysis, and molecular analysis.


Journal Article

Amebic infections involving the central nervous system are rare and difficult to diagnose. Magnetic resonance imaging (MRI) at timed intervals may be helpful, where scans reveal enhancing lesions and increased signal. We report a unique case of granulomatous amebic encephalitis that was proven pathologically with progressive radiological findings on MRI.

Full Text

Duke Authors

Cited Authors

  • McKellar, MS; Mehta, LR; Greenlee, JE; Hale, DC; Booton, GC; Kelly, DJ; Fuerst, PA; Sriram, R; Visvesvara, GS

Published Date

  • November 2006

Published In

Volume / Issue

  • 44 / 11

Start / End Page

  • 4265 - 4269

PubMed ID

  • 16988022

Pubmed Central ID

  • 16988022

International Standard Serial Number (ISSN)

  • 0095-1137

Digital Object Identifier (DOI)

  • 10.1128/JCM.00649-06


  • eng

Conference Location

  • United States