Temporal lobe epilepsy and the BDNF receptor, TrkB
Publication
, Journal Article
McNamara, JO; Scharfman, HE
Published in: Epilepsia
December 1, 2010
Brain derived neurotrophic factor (BDNF) regulates diverse neuronal functions and plasticity, and its expression is increased by seizures. Here we review the evidence that actions of BDNF at TrkB receptors contribute to temporal lobe epilepsy. In addition, regulation of BDNF by steroid hormones might explain syndromes such as catamenial epilepsy. For an expanded treatment of this topic see Jasper's Basic Mechanisms of the Epilepsies, Fourth Edition (Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, eds) published by Oxford University Press (available on the National Library of Medicine Bookshelf [NCBI] at). © 2010 International League Against Epilepsy.
Duke Scholars
Published In
Epilepsia
DOI
EISSN
1528-1167
ISSN
0013-9580
Publication Date
December 1, 2010
Volume
51
Issue
SUPPL. 5
Start / End Page
46
Related Subject Headings
- Neurology & Neurosurgery
- 3209 Neurosciences
- 3202 Clinical sciences
- 1109 Neurosciences
- 1103 Clinical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
McNamara, J. O., & Scharfman, H. E. (2010). Temporal lobe epilepsy and the BDNF receptor, TrkB. Epilepsia, 51(SUPPL. 5), 46. https://doi.org/10.1111/j.1528-1167.2010.02832.x
McNamara, J. O., and H. E. Scharfman. “Temporal lobe epilepsy and the BDNF receptor, TrkB.” Epilepsia 51, no. SUPPL. 5 (December 1, 2010): 46. https://doi.org/10.1111/j.1528-1167.2010.02832.x.
McNamara JO, Scharfman HE. Temporal lobe epilepsy and the BDNF receptor, TrkB. Epilepsia. 2010 Dec 1;51(SUPPL. 5):46.
McNamara, J. O., and H. E. Scharfman. “Temporal lobe epilepsy and the BDNF receptor, TrkB.” Epilepsia, vol. 51, no. SUPPL. 5, Dec. 2010, p. 46. Scopus, doi:10.1111/j.1528-1167.2010.02832.x.
McNamara JO, Scharfman HE. Temporal lobe epilepsy and the BDNF receptor, TrkB. Epilepsia. 2010 Dec 1;51(SUPPL. 5):46.
Published In
Epilepsia
DOI
EISSN
1528-1167
ISSN
0013-9580
Publication Date
December 1, 2010
Volume
51
Issue
SUPPL. 5
Start / End Page
46
Related Subject Headings
- Neurology & Neurosurgery
- 3209 Neurosciences
- 3202 Clinical sciences
- 1109 Neurosciences
- 1103 Clinical Sciences