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Strategies used in the detection of acute/early HIV infections. The NIMH Multisite Acute HIV Infection Study: I.

Publication ,  Journal Article
Kerndt, PR; Dubrow, R; Aynalem, G; Mayer, KH; Beckwith, C; Remien, RH; Truong, H-HM; Uniyal, A; Chien, M; Brooks, RA; Vigil, OR; Steward, WT ...
Published in: AIDS Behav
December 2009

Acute/early HIV infection plays a critical role in onward HIV transmission. Detection of HIV infections during this period provides an important early opportunity to offer interventions which may prevent further transmission. In six US cities, persons with acute/early HIV infection were identified using either HIV RNA testing of pooled sera from persons screened HIV antibody negative or through clinical referral of persons with acute or early infections. Fifty-one cases were identified and 34 (68%) were enrolled into the study; 28 (82%) were acute infections and 6 (18%) were early infections. Of those enrolled, 13 (38%) were identified through HIV pooled testing of 7,633 HIV antibody negative sera and 21 (62%) through referral. Both strategies identified cases that would have been missed under current HIV testing and counseling protocols. Efforts to identify newly infected persons should target specific populations and geographic areas based on knowledge of the local epidemiology of incident infections.

Duke Scholars

Published In

AIDS Behav

DOI

EISSN

1573-3254

Publication Date

December 2009

Volume

13

Issue

6

Start / End Page

1037 / 1045

Location

United States

Related Subject Headings

  • Young Adult
  • United States
  • Reverse Transcriptase Polymerase Chain Reaction
  • Referral and Consultation
  • RNA, Viral
  • Public Health
  • Public Health
  • National Institute of Mental Health (U.S.)
  • Male
  • Humans
 

Citation

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Chicago
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MLA
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Kerndt, P. R., Dubrow, R., Aynalem, G., Mayer, K. H., Beckwith, C., Remien, R. H., … Morin, S. F. (2009). Strategies used in the detection of acute/early HIV infections. The NIMH Multisite Acute HIV Infection Study: I. AIDS Behav, 13(6), 1037–1045. https://doi.org/10.1007/s10461-009-9580-8
Kerndt, Peter R., Robert Dubrow, Getahun Aynalem, Kenneth H. Mayer, Curt Beckwith, Robert H. Remien, Hong-Ha M. Truong, et al. “Strategies used in the detection of acute/early HIV infections. The NIMH Multisite Acute HIV Infection Study: I.AIDS Behav 13, no. 6 (December 2009): 1037–45. https://doi.org/10.1007/s10461-009-9580-8.
Kerndt PR, Dubrow R, Aynalem G, Mayer KH, Beckwith C, Remien RH, et al. Strategies used in the detection of acute/early HIV infections. The NIMH Multisite Acute HIV Infection Study: I. AIDS Behav. 2009 Dec;13(6):1037–45.
Kerndt, Peter R., et al. “Strategies used in the detection of acute/early HIV infections. The NIMH Multisite Acute HIV Infection Study: I.AIDS Behav, vol. 13, no. 6, Dec. 2009, pp. 1037–45. Pubmed, doi:10.1007/s10461-009-9580-8.
Kerndt PR, Dubrow R, Aynalem G, Mayer KH, Beckwith C, Remien RH, Truong H-HM, Uniyal A, Chien M, Brooks RA, Vigil OR, Steward WT, Merson M, Rotheram-Borus MJ, Morin SF. Strategies used in the detection of acute/early HIV infections. The NIMH Multisite Acute HIV Infection Study: I. AIDS Behav. 2009 Dec;13(6):1037–1045.
Journal cover image

Published In

AIDS Behav

DOI

EISSN

1573-3254

Publication Date

December 2009

Volume

13

Issue

6

Start / End Page

1037 / 1045

Location

United States

Related Subject Headings

  • Young Adult
  • United States
  • Reverse Transcriptase Polymerase Chain Reaction
  • Referral and Consultation
  • RNA, Viral
  • Public Health
  • Public Health
  • National Institute of Mental Health (U.S.)
  • Male
  • Humans