Oral rehydration therapy for treatment of rotavirus diarrhoea in a rural treatment centre in Bangladesh.

Journal Article (Journal Article)

In November 1977, an enzyme-linked immunosorbent assay for detecting rotavirus antigen was introduced in the laboratory of a rural treatment centre in Bangladesh. During the next 40 days rotavirus without other pathogens was found in the stools of 216 (45%) of 480 children under age 5 years who visited the centre with a gastrointestinal illness. 188 (87%) of these children were treated with oral rehydration alone, using the solution currently recommended by the World Health Organisation, while 28 (13%) also required some intravenous rehydration; there were no deaths. Oral rehydration treatment was judged successful in 205 (95%) of the rotavirus patients and was not associated with any serious side effects. Oral rehydration treatment, with this solution, has been used extensively and successfully in the treatment of enterotoxin-mediated diarrhoea and can also safely be used for treating rotavirus diarrhoea in infants and young children.

Full Text

Duke Authors

Cited Authors

  • Taylor, PR; Merson, MH; Black, RE; Mizanur Rahman, AS; Yunus, MD; Alim, AR; Yolken, RH

Published Date

  • May 1980

Published In

Volume / Issue

  • 55 / 5

Start / End Page

  • 376 - 379

PubMed ID

  • 6254447

Pubmed Central ID

  • PMC1626870

Electronic International Standard Serial Number (EISSN)

  • 1468-2044

Digital Object Identifier (DOI)

  • 10.1136/adc.55.5.376


  • eng

Conference Location

  • England