Relationship between enterotoxin production and serotype in enterotoxigenic Escherichia coli.

Journal Article

We examined the relationship between serotype and enterotoxin production in 109 enterotoxigenic Escherichia coli strains isolated from 109 patients with severe cholera-like diarrhea in Dacca, Bangladesh. Of 69 strains producing both heat-labile and heat-stable toxins, 59 (86%) belonged to the one of four O serogroups, and 56 (81%) of these strains belonged to one of six O:K:H serotypes. In contrast, 34 strains producing only heat-stable toxin were distributed among 15 O serogroups, and six strains producing only heat-labile toxin were distributed among six O serogroups. Twelve strains producing heat-labile and heat-stable toxins and five strains producing heat-stable toxin were found which had the same serotype (O78:K-:H12) and biotype. It appears that at least in one geographic setting E. coli strains producing both heat-labile and heat-stable toxins are more restricted in their O groups and O:K:H serotypes than E. coli that produce only heat-stable toxin and that certain serobiotypes may commonly include strains which produce both toxin types.

Full Text

Duke Authors

Cited Authors

  • Merson, MH; Orskov, F; Orskov, I; Sack, RB; Huq, I; Koster, FT

Published Date

  • February 1, 1979

Published In

Volume / Issue

  • 23 / 2

Start / End Page

  • 325 - 329

PubMed ID

  • 370013

International Standard Serial Number (ISSN)

  • 0019-9567

Language

  • eng

Conference Location

  • United States