Goal-directed or goal-misdirected - how should we interpret the literature?

Journal Article (Journal Article)

Goal-directed therapy (GDT) can be a vague term, meaning different things to different people and, depending on the clinical environment, sometimes even different things to the same person. It can refer to perioperative fluid management, clinicians driving oxygen delivery to supramaximal values, early treatment of sepsis in the emergency department, and even to restriction of perioperative crystalloids with the goal of maintaining preadmission body weight. Understandably, strong opinions about GDT vary; some clinicians consider it essential for perioperative care, others completely ineffective in critically ill patients. This commentary aims to further position the excellent review by Lees and colleagues in the context of the critical care and perioperative setting.

Full Text

Duke Authors

Cited Authors

  • Roche, AM; Miller, TE

Published Date

  • 2010

Published In

Volume / Issue

  • 14 / 2

Start / End Page

  • 129 -

PubMed ID

  • 20236472

Pubmed Central ID

  • PMC2887118

Electronic International Standard Serial Number (EISSN)

  • 1466-609X

Digital Object Identifier (DOI)

  • 10.1186/cc8884


  • eng

Conference Location

  • England