Early thinking on the nature of mismatch repair

Journal Article (Journal Article)

Replication error correction by mismatch repair relies on the strand-directed nature of the reaction. Ephrussi-Taylor and Gray attributed the marker-dependent recovery of pneumoccocal transformants to a mismatch-provoked repair reaction characterized by a strong strand bias and long excision tracts. This idea was extended by Wagner and Meselson in the context of a study on mismatch repair of multiply marked lambda heteroduplexes, with the explicit proposal that strand-directed mismatch repair could provide a mechanism for correcting DNA biosynthetic errors. © 2004 Elsevier B.V. All rights reserved.

Full Text

Duke Authors

Cited Authors

  • Modrich, P

Published Date

  • January 2, 2005

Published In

Volume / Issue

  • 4 / 1

Start / End Page

  • 103 - 131

International Standard Serial Number (ISSN)

  • 1568-7864

Digital Object Identifier (DOI)

  • 10.1016/j.dnarep.2004.07.002

Citation Source

  • Scopus