Studies on sequence recognition by type II restriction and modification enzymes.
Published
Journal Article (Review)
Type II DNA restriction and modification systems are ideally suited for analysis of mechanisms by which proteins specifically recognize unique DNA sequences. Each system is comprised of a unique DNA recognition site and two enzymes, which in those cases examined in detail, are comprised of distinct polypeptide chains. Thus, not only are the DNA substrates extremely well defined, but each system affords the opportunity to compare distinct proteins which interact with a common DNA sequence. This review will focus only on those Type II systems which have been examined in sufficient molecular detail to permit some insight into modes of specific DNA-protein interaction.
Full Text
Duke Authors
Cited Authors
- Modrich, P
Published Date
- 1982
Published In
Volume / Issue
- 13 / 3
Start / End Page
- 287 - 323
PubMed ID
- 6293768
Pubmed Central ID
- 6293768
International Standard Serial Number (ISSN)
- 0045-6411
Digital Object Identifier (DOI)
- 10.3109/10409238209114231
Language
- eng
Conference Location
- United States