Partial NH2- and cooh-terminal sequence analyses of Eco RI DNA restriction and modification enzymes.


Journal Article

NH2- and COOH-terminal amino acid sequences of the Eco RI restriction and modification enzymes have been determined. The results allow localization of the coding regions within the DNA segment which controls activity of both enzymes. Processing of the endonuclease is limited to removal of NH2-terminal formylmethionine whereas, in the case of the methylase, formylMet-Ala is removed.

Full Text

Duke Authors

Cited Authors

  • Rubin, RA; Modrich, P; Vanaman, TC

Published Date

  • March 10, 1981

Published In

Volume / Issue

  • 256 / 5

Start / End Page

  • 2140 - 2142

PubMed ID

  • 6257702

Pubmed Central ID

  • 6257702

International Standard Serial Number (ISSN)

  • 0021-9258


  • eng

Conference Location

  • United States