DNA priming and recombinant pox virus boosters for an AIDS vaccine.

Journal Article

Eight different protocols for immunization have been compared for the ability to raise protection against immunodeficiency virus challenges in rhesus macaques. The most promising containment of challenge infections was achieved by intradermal DNA priming followed by recombinant fowl pox virus booster immunizations. This containment did not require neutralizing antibody and was active for a series of challenges ending with a highly virulent virus with a primary isolate envelope heterologous to the immunizing strain.

Full Text

Duke Authors

Cited Authors

  • Robinson, HL; Montefiori, DC; Johnson, RP; Kalish, ML; Lydy, SL; McClure, HM

Published Date

  • 2000

Published In

Volume / Issue

  • 104 /

Start / End Page

  • 93 - 100

PubMed ID

  • 11713830

International Standard Serial Number (ISSN)

  • 1424-6074

Language

  • eng

Conference Location

  • Switzerland