Synthesis of phenanthridin-3-one derivatives: Non-steroidal inhibitors of steroid 5-α-reductase
Journal Article (Journal Article)
A short and efficient six-step synthesis of novel phenanthridin-3-one derivatives is described. The synthesis of these derivatives is highlighted by the cyclization of a suitably placed ketone side chain with a thioiminium ion. The derivatives prepared were found to be inhibitors of human steroid 5-α-reductase. © 1995.
Full Text
Duke Authors
Cited Authors
- Mook, RA; Lackey, K; Bennett, C
Published Date
- June 5, 1995
Published In
Volume / Issue
- 36 / 23
Start / End Page
- 3969 - 3972
International Standard Serial Number (ISSN)
- 0040-4039
Digital Object Identifier (DOI)
- 10.1016/0040-4039(95)00690-E
Citation Source
- Scopus