Manipulation of a central auditory representation shapes learned vocal output.

Published

Journal Article

Learned vocalizations depend on the ear's ability to monitor and ultimately instruct the voice. Where is auditory feedback processed in the brain, and how does it modify motor networks for learned vocalizations? Here we addressed these questions using singing-triggered microstimulation and chronic recording methods in the singing zebra finch, a small songbird that relies on auditory feedback to learn and maintain its species-typical vocalizations. Manipulating the singing-related activity of feedback-sensitive thalamic neurons subsequently triggered vocal plasticity, constraining the central pathway and functional mechanisms through which feedback-related information shapes vocalization.

Full Text

Duke Authors

Cited Authors

  • Lei, H; Mooney, R

Published Date

  • January 14, 2010

Published In

Volume / Issue

  • 65 / 1

Start / End Page

  • 122 - 134

PubMed ID

  • 20152118

Pubmed Central ID

  • 20152118

Electronic International Standard Serial Number (EISSN)

  • 1097-4199

Digital Object Identifier (DOI)

  • 10.1016/j.neuron.2009.12.008

Language

  • eng

Conference Location

  • United States