Hodgkin lymphoma, version 2.2012 featured updates to the NCCN guidelines.

Journal Article (Journal Article)

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Hodgkin Lymphoma (HL) include the clinical management of classical HL and lymphocyte-predominant HL (LPHL). Major changes have been incorporated into these guidelines since their inception. In the 2012 NCCN Guidelines for HL, PET scans are not recommended for interim restaging of patients with stage I to II favorable disease. After reevaluating the available evidence on the use of interim PET imaging, the panel recommends the use of diagnostic CT scan of involved sites for interim restaging after completion of chemotherapy for this group of patients. Maintenance rituximab for 2 years is included as an option for patients with stage IB to IIB or stage III to IV LPHL treated with rituximab alone in the first-line setting. Brentuximab vedotin is included as an option for patients with progressive disease or relapsed disease after second-line chemotherapy or high-dose therapy with autologous stem cell rescue.

Full Text

Duke Authors

Cited Authors

  • Hoppe, RT; Advani, RH; Ai, WZ; Ambinder, RF; Aoun, P; Bello, CM; Bierman, PJ; Blum, KA; Chen, R; Dabaja, B; Duron, Y; Forero, A; Gordon, LI; Hernandez-Ilizaliturri, FJ; Hochberg, EP; Maloney, DG; Mansur, D; Mauch, PM; Metzger, M; Moore, JO; Morgan, D; Moskowitz, CH; Poppe, M; Pro, B; Winter, JN; Yahalom, J; Sundar, H; National Comprehensive Cancer Network,

Published Date

  • May 2012

Published In

Volume / Issue

  • 10 / 5

Start / End Page

  • 589 - 597

PubMed ID

  • 22570290

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2012.0061


  • eng

Conference Location

  • United States