A case of frontal neuropsychological and neuroimaging signs following multiple primary-blast exposure.

Journal Article (Journal Article)

Blast-related traumatic brain injury (TBI) from the Afghanistan and Iraq wars represents a significant medical concern for troops and veterans. To better understand the consequences of primary-blast injury in humans, we present a case of a Marine exposed to multiple primary blasts during his 14-year military career. The neuropsychological profile of this formerly high-functioning veteran suggested primarily executive dysfunction. Diffusion-tensor imaging revealed white-matter pathology in long fiber tracks compared with a composite fractional-anisotropy template derived from a veteran reference control group without TBI. This study supports the existence of primary blast-induced neurotrauma in humans and introduces a neuroimaging technique with potential to discriminate multiple-blast TBI.

Full Text

Duke Authors

Cited Authors

  • Hayes, JP; Morey, RA; Tupler, LA

Published Date

  • June 2012

Published In

Volume / Issue

  • 18 / 3

Start / End Page

  • 258 - 269

PubMed ID

  • 21879996

Pubmed Central ID

  • PMC3718065

Electronic International Standard Serial Number (EISSN)

  • 1465-3656

Digital Object Identifier (DOI)

  • 10.1080/13554794.2011.588181


  • eng

Conference Location

  • England