Nanoscale separations. Capillary liquid chromatography-mass spectrometry and capillary zone electrophoresis-mass spectrometry for the determination of peptides and proteins


Journal Article

Nanoscale separation techniques, such as packed capillary liquid chromatography and capillary zone electrophoresis in which the column effluent flow-rates are in the nanoliter per minute range rather than microliter per minute range, have been successfully interfaced with continuous-flow fast atom bombardment and electrospray ionization. Applications of these techniques to the separation and determination of peptide mixtures, protein digests and protein mixtures are presented. © 1991.

Full Text

Duke Authors

Cited Authors

  • Deterding, LJ; Parker, CE; Perkins, JR; Arthur Moseley, M; Jorgenson, JW; Tomer, KB

Published Date

  • August 21, 1991

Published In

Volume / Issue

  • 554 / 1-2

Start / End Page

  • 329 - 338

International Standard Serial Number (ISSN)

  • 0021-9673

Digital Object Identifier (DOI)

  • 10.1016/S0021-9673(01)88460-0

Citation Source

  • Scopus