Nanoscale separations. Capillary liquid chromatography-mass spectrometry and capillary zone electrophoresis-mass spectrometry for the determination of peptides and proteins

Journal Article (Journal Article)

Nanoscale separation techniques, such as packed capillary liquid chromatography and capillary zone electrophoresis in which the column effluent flow-rates are in the nanoliter per minute range rather than microliter per minute range, have been successfully interfaced with continuous-flow fast atom bombardment and electrospray ionization. Applications of these techniques to the separation and determination of peptide mixtures, protein digests and protein mixtures are presented. © 1991.

Full Text

Duke Authors

Cited Authors

  • Deterding, LJ; Parker, CE; Perkins, JR; Arthur Moseley, M; Jorgenson, JW; Tomer, KB

Published Date

  • August 21, 1991

Published In

Volume / Issue

  • 554 / 1-2

Start / End Page

  • 329 - 338

International Standard Serial Number (ISSN)

  • 0021-9673

Digital Object Identifier (DOI)

  • 10.1016/S0021-9673(01)88460-0

Citation Source

  • Scopus