Nanoscale separations combined with tandem mass spectrometry.
Publication
, Journal Article
Deterding, LJ; Moseley, MA; Tomer, KB; Jorgenson, JW
Published in: J Chromatogr
August 21, 1991
High-efficiency separations of peptide mixtures, tryptic digest and other biological compounds have been achieved using nanoscale packed capillaries and capillary zone electrophoresis (CZE). The coaxial continuous-flow fast atom bombardment design is an excellent interface for coupling these separation techniques with mass spectrometry (MS). In addition, this interface is very useful for the acquisition of MS-MS data from compounds separated by nanoscale packed capillary liquid chromatography and CZE. Structurally informative daughter-ion spectra can be obtained at the low picomole to femtomole level.
Duke Scholars
Published In
J Chromatogr
DOI
Publication Date
August 21, 1991
Volume
554
Issue
1-2
Start / End Page
73 / 82
Location
Netherlands
Related Subject Headings
- Trypsin
- Spectrometry, Mass, Fast Atom Bombardment
- Peptide Fragments
- Molecular Sequence Data
- Microchemistry
- Mass Spectrometry
- Growth Hormone-Releasing Hormone
- Electrophoresis
- Cytochrome c Group
- Cosyntropin
Citation
APA
Chicago
ICMJE
MLA
NLM
Deterding, L. J., Moseley, M. A., Tomer, K. B., & Jorgenson, J. W. (1991). Nanoscale separations combined with tandem mass spectrometry. J Chromatogr, 554(1–2), 73–82. https://doi.org/10.1016/s0021-9673(01)88438-7
Deterding, L. J., M. A. Moseley, K. B. Tomer, and J. W. Jorgenson. “Nanoscale separations combined with tandem mass spectrometry.” J Chromatogr 554, no. 1–2 (August 21, 1991): 73–82. https://doi.org/10.1016/s0021-9673(01)88438-7.
Deterding LJ, Moseley MA, Tomer KB, Jorgenson JW. Nanoscale separations combined with tandem mass spectrometry. J Chromatogr. 1991 Aug 21;554(1–2):73–82.
Deterding, L. J., et al. “Nanoscale separations combined with tandem mass spectrometry.” J Chromatogr, vol. 554, no. 1–2, Aug. 1991, pp. 73–82. Pubmed, doi:10.1016/s0021-9673(01)88438-7.
Deterding LJ, Moseley MA, Tomer KB, Jorgenson JW. Nanoscale separations combined with tandem mass spectrometry. J Chromatogr. 1991 Aug 21;554(1–2):73–82.
Published In
J Chromatogr
DOI
Publication Date
August 21, 1991
Volume
554
Issue
1-2
Start / End Page
73 / 82
Location
Netherlands
Related Subject Headings
- Trypsin
- Spectrometry, Mass, Fast Atom Bombardment
- Peptide Fragments
- Molecular Sequence Data
- Microchemistry
- Mass Spectrometry
- Growth Hormone-Releasing Hormone
- Electrophoresis
- Cytochrome c Group
- Cosyntropin