Evidence-ranked motif identification.
Publication
, Journal Article
Georgiev, S; Boyle, AP; Jayasurya, K; Ding, X; Mukherjee, S; Ohler, U
Published in: Genome Biol
2010
cERMIT is a computationally efficient motif discovery tool based on analyzing genome-wide quantitative regulatory evidence. Instead of pre-selecting promising candidate sequences, it utilizes information across all sequence regions to search for high-scoring motifs. We apply cERMIT on a range of direct binding and overexpression datasets; it substantially outperforms state-of-the-art approaches on curated ChIP-chip datasets, and easily scales to current mammalian ChIP-seq experiments with data on thousands of non-coding regions.
Duke Scholars
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Published In
Genome Biol
DOI
EISSN
1474-760X
Publication Date
2010
Volume
11
Issue
2
Start / End Page
R19
Location
England
Related Subject Headings
- Sequence Analysis, DNA
- Oligonucleotide Array Sequence Analysis
- Mice
- Humans
- Genome-Wide Association Study
- Genome, Human
- DNA, Fungal
- Computational Biology
- Bioinformatics
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Georgiev, S., Boyle, A. P., Jayasurya, K., Ding, X., Mukherjee, S., & Ohler, U. (2010). Evidence-ranked motif identification. Genome Biol, 11(2), R19. https://doi.org/10.1186/gb-2010-11-2-r19
Georgiev, Stoyan, Alan P. Boyle, Karthik Jayasurya, Xuan Ding, Sayan Mukherjee, and Uwe Ohler. “Evidence-ranked motif identification.” Genome Biol 11, no. 2 (2010): R19. https://doi.org/10.1186/gb-2010-11-2-r19.
Georgiev S, Boyle AP, Jayasurya K, Ding X, Mukherjee S, Ohler U. Evidence-ranked motif identification. Genome Biol. 2010;11(2):R19.
Georgiev, Stoyan, et al. “Evidence-ranked motif identification.” Genome Biol, vol. 11, no. 2, 2010, p. R19. Pubmed, doi:10.1186/gb-2010-11-2-r19.
Georgiev S, Boyle AP, Jayasurya K, Ding X, Mukherjee S, Ohler U. Evidence-ranked motif identification. Genome Biol. 2010;11(2):R19.
Published In
Genome Biol
DOI
EISSN
1474-760X
Publication Date
2010
Volume
11
Issue
2
Start / End Page
R19
Location
England
Related Subject Headings
- Sequence Analysis, DNA
- Oligonucleotide Array Sequence Analysis
- Mice
- Humans
- Genome-Wide Association Study
- Genome, Human
- DNA, Fungal
- Computational Biology
- Bioinformatics
- Animals