[Endogenous inhibitors of specific benzodiazepine binding in the cerebral cortex of the bull].
Journal Article (English Abstract;Journal Article)
Chromatography of an acidic extract from bovine brain cortex on a Sephadex G-10 column demonstrated 7 fractions capable of inhibiting specific binding of 3H-diazepam to brain cortex membranes. It was established by ultrafiltration that the molecular weights of the inhibitors were not higher than 5000 dalton. Scatchard analysis of 4 main fractions has revealed a type of inhibition similar to the competitive one. Activity of all the fractions remained unchanged after pronase treatment.
Full Text
Duke Authors
Cited Authors
- Kladnitskiĭ, AV; Mukhin, AG
Published Date
- October 1, 1984
Published In
Volume / Issue
- 98 / 10
Start / End Page
- 439 - 441
PubMed ID
- 6149775
International Standard Serial Number (ISSN)
- 0365-9615
Language
- rus
Conference Location
- Russia (Federation)