Generalized papular xanthomatosis in mycosis fungoides

Published

Journal Article

Xanthomas can occur in association with underlying lymphoproliferative disease, or they can result from lipid deposition in damaged or altered skin. We report a case of generalized papular xanthomas that developed in a patient with Sézary syndrome. The xanthomas were composed of foamy histiocytes that were shown by immunoperoxidase staining to be of the monocyte/macrophage lineage. Electron microscopic studies revealed lipid vacuoles, lysos-ornes, and myelin figures but no Birbeck granules, features that are consistent with a non-X histiocytosis. Generalized papular xanthomatosis has not been previously described in a patient with cutaneous T-cell lymphoma. © 1992, American Academy of Dermatology, Inc. All rights reserved.

Full Text

Duke Authors

Cited Authors

  • Darwin, BS; Herzberg, AJ; Murray, JC; Olsen, EA

Published Date

  • January 1, 1992

Published In

Volume / Issue

  • 26 / 5

Start / End Page

  • 828 - 832

International Standard Serial Number (ISSN)

  • 0190-9622

Digital Object Identifier (DOI)

  • 10.1016/0190-9622(92)70115-V

Citation Source

  • Scopus