Studies on the psychopharmacological activities of Rumex nepalensis Spreng. root extract in rats and mice.


Journal Article

The methanol extract of Rumex nepalensis Spreng. (Family - Polygonaceae) was assessed for different psychopharmacological activities in rats and mice by evaluation of general behaviour, exploratory behaviour, muscle relaxant activity and phenobarbitone sodium-induced sleeping time. The extract at doses 200 mg/kg and above exhibited a reduction in spontaneous activity (general behavioural profile), a decrease in exploratory behavioural pattern in the Y-maze and Head-dip tests, a reduction in muscle relaxant activity in rotarod, 30 degrees inclined screen and traction tests, and also potentiated phenobarbitone sodium-induced sleeping time.

Full Text

Duke Authors

Cited Authors

  • Ghosh, L; Arunachalam, G; Murugesan, T; Pal, M; Saha, BP

Published Date

  • April 2002

Published In

Volume / Issue

  • 9 / 3

Start / End Page

  • 202 - 206

PubMed ID

  • 12046859

Pubmed Central ID

  • 12046859

International Standard Serial Number (ISSN)

  • 0944-7113

Digital Object Identifier (DOI)

  • 10.1078/0944-7113-00115


  • eng

Conference Location

  • Germany