Evaluation of anti-pyretic potential of Jussiaea suffruticosa L. extract in rats.

Published

Journal Article

A study was carried out to evaluate the anti-pyretic potential of the methanol extract of the aerial part of Jussiaea suffruticosa Linn. (MEJS) on normal body temperature and yeast-induced pyrexia in albino rats. Yeast suspension (10 ml/kg body wt.) increased rectal temperature after 19 hours of subcutaneous injection. The MEJS, at doses of 100, 200 and 300 mg/kg body wt. p.o., showed significant reduction in normal body temperature and yeast-provoked elevated temperature in a dose-dependent manner. The effect also extended up to 5 hours after the drug administration. The anti-pyretic effect of MEJS was comparable to that of paracetamol (150 mg/kg body wt, p.o.), a standard anti-pyretic agent.

Full Text

Duke Authors

Cited Authors

  • Murugesan, T; Mandal, SC; Bhakta, T; Das, J; Pal, M; Saha, BP

Published Date

  • June 2000

Published In

Volume / Issue

  • 7 / 3

Start / End Page

  • 231 - 234

PubMed ID

  • 11185734

Pubmed Central ID

  • 11185734

International Standard Serial Number (ISSN)

  • 0944-7113

Digital Object Identifier (DOI)

  • 10.1016/S0944-7113(00)80008-2

Language

  • eng

Conference Location

  • Germany