Evaluation of antidiarrhoeal profile of Jussiaea suffruticosa linn. extract in rats.


Journal Article

The antidiarrhoeal potential of a methanol extract of the aerial parts of Jussiaea suffruticosa Linn. (MEJS) was studied with several experimental models of diarrhoea in rats. MEJS treated rats showed significant inhibitory activity against castor oil induced diarrhoea and PGE(2) induced enteropooling. It also showed a significant reduction in gastrointestinal motility following a charcoal meal in rats. The extract exhibited significant antidiarrhoeal potential at doses of 100,200 and 300 mg/kg in all the animal models and thus established the efficacy of MEJS as a potent antidiarrhoeal agent.

Full Text

Duke Authors

Cited Authors

  • Murugesan, T; Ghosh, L; Mukherjee, K; Das, J; Pal, M; Saha, BP

Published Date

  • August 2000

Published In

Volume / Issue

  • 14 / 5

Start / End Page

  • 381 - 383

PubMed ID

  • 10925410

Pubmed Central ID

  • 10925410

International Standard Serial Number (ISSN)

  • 0951-418X


  • eng

Conference Location

  • England