Evaluation of antitussive potential of Jussiaea suffruticosa linn. extract in albino mice.


Journal Article

The antitussive activity of a methanol extract of Jussiaea suffruticosa Linn. (MEJS) (family Onagraceae) leaves has been evaluated for its potential on a cough induced by sulphur dioxide (SO(2)) gas model in mice. The extract (MEJS) showed significant antitussive activity in a dose dependent manner. The antitussive potential of MEJS was comparable to that of codeine phosphate (10 mg/kg), a standard drug. The extract (MEJS) at a dose level of 200 and 400 mg/kg, p.o. showed appreciable inhibition on the cough reflex by 48.52% and 59.8% respectively during 120 min of the experiment.

Full Text

Cited Authors

  • Murugesan, T; Ghosh, L; Mukherjee, PK; Pal, M; Saha, BP

Published Date

  • November 2000

Published In

Volume / Issue

  • 14 / 7

Start / End Page

  • 541 - 542

PubMed ID

  • 11054846

Pubmed Central ID

  • 11054846

International Standard Serial Number (ISSN)

  • 0951-418X

Digital Object Identifier (DOI)

  • 10.1002/1099-1573(200011)14:7<541::aid-ptr637>3.0.co;2-3


  • eng

Conference Location

  • England