Anti-diarrhoeal evaluation of Clerodendrum phlomidis Linn. leaf extract in rats.


Journal Article

A study was undertaken to evaluate the effect of methanolic extract of leaves of Clerodendrum phlomidis Linn. (MECP) (Family: Verbenaceae) for its anti-diarrhoeal potential against several experimental models of diarrhoea in Wistar albino rats. MECP showed significant inhibitory activity against castor oil induced diarrhoea and PGE2 induced enteropooling in rats. The extract also showed a significant reduction in gastrointestinal motility in charcoal meal test in rats. The results obtained establish the efficacy and substantiated the folklore claim as an anti-diarrhoeal agent.

Full Text

Cited Authors

  • Rani, S; Ahamed, N; Rajaram, S; Saluja, R; Thenmozhi, S; Murugesan, T

Published Date

  • December 15, 1999

Published In

Volume / Issue

  • 68 / 1-3

Start / End Page

  • 315 - 319

PubMed ID

  • 10624894

Pubmed Central ID

  • 10624894

International Standard Serial Number (ISSN)

  • 0378-8741

Digital Object Identifier (DOI)

  • 10.1016/s0378-8741(99)00103-8


  • eng

Conference Location

  • Ireland