Studies on in vivo antitussive activity of Leucas lavandulaefolia using a cough model induced by sulfur dioxide gas in mice.


Journal Article

The methanol extract of Leucas lavandulaefolia was investigated for its effects on a cough model induced by sulfur dioxide gas in mice. It exhibited significant antitussive activity when compared with control in a dose-dependent manner. The antitussive activity of the extract was comparable to that of codeine phosphate (10 mg/kg), a prototype antitussive agent. The Leucas lavandulaefolia extract at 100, 200, and 400 mg/kg. p.o. showed inhibition of cough by 35.0, 51.9, and 56.5% within 1 h of performing the experiment.

Full Text

Duke Authors

Cited Authors

  • Saha, K; Mukherjee, PK; Murugesan, T; Saha, BP; Pal, M

Published Date

  • July 1997

Published In

Volume / Issue

  • 57 / 2

Start / End Page

  • 89 - 92

PubMed ID

  • 9254111

Pubmed Central ID

  • 9254111

International Standard Serial Number (ISSN)

  • 0378-8741

Digital Object Identifier (DOI)

  • 10.1016/s0378-8741(97)00050-0


  • eng

Conference Location

  • Ireland