Pruritus in systemic disease: mechanisms and management.


Journal Article (Review)

Pruritus is the most common symptom of skin disease. Even in the absence of primary cutaneous findings, severe and extensive pruritus often is associated with systemic disease. This review considers briefly the physiology of pruritus and discusses the various systemic diseases often accompanied by this bothersome symptom. In addition to exploring the possible mechanisms and potential therapies of itching in selected disorders, this review presents general recommendations for evaluating patients with unexplained pruritus and management guidelines for alleviating their discomfort.

Full Text

Duke Authors

Cited Authors

  • Etter, L; Myers, SA

Published Date

  • July 2002

Published In

Volume / Issue

  • 20 / 3

Start / End Page

  • 459 - vii

PubMed ID

  • 12170879

Pubmed Central ID

  • 12170879

International Standard Serial Number (ISSN)

  • 0733-8635


  • eng

Conference Location

  • United States