Plasticity of glutamate synaptic mechanisms

Journal Article (Journal Article)

Enhanced glutamate synaptic transmission may be expected to alter the balance of excitation and inhibition in brain, leading to seizures. Several differences between epileptic and nonepileptic brains in presynaptic and postsynaptic glutamate mechanisms have been reported. These findings suggest that altered glutamate mechanisms contribute to the hyperexcitability of epileptic brain. For an expanded treatment of this topic see Jasper's Basic Mechanisms of the Epilepsies, Fourth Edition (Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, eds) published by Oxford University Press (available on the National Library of Medicine Bookshelf [NCBI] at). © 2010 International League Against Epilepsy.

Full Text

Duke Authors

Cited Authors

  • Victor Nadler, J

Published Date

  • December 1, 2010

Published In

Volume / Issue

  • 51 / SUPPL. 5

Start / End Page

  • 17 -

Electronic International Standard Serial Number (EISSN)

  • 1528-1167

International Standard Serial Number (ISSN)

  • 0013-9580

Digital Object Identifier (DOI)

  • 10.1111/j.1528-1167.2010.02803.x

Citation Source

  • Scopus