Seizure-induced basal dendrites on granule cells

Journal Article (Journal Article)

Seizure-induced hilar basal dendrites on dentate granule cells are observed in several rodent models of temporal lobe epilepsy. Ultrastructural evidence showed that basal dendrites receive predominantly excitatory synapses, including many from mossy fibers. Such highly interconnected granule cells with basal dendrites are suggested to enhance hyperexcitability within the dentate network. For an expanded treatment of this topic see Jasper's Basic Mechanisms of the Epilepsies, Fourth Edition (Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, eds) published by Oxford University Press (available on the National Library of Medicine Bookshelf [NCBI] at). © 2010 International League Against Epilepsy.

Full Text

Duke Authors

Cited Authors

  • Ribak, CE; Shapiro, LA; Yan, XX; Dashtipour, K; Nadler, JV; Obenaus, A; Spigelman, I; Buckmaster, PS

Published Date

  • December 1, 2010

Published In

Volume / Issue

  • 51 / SUPPL. 5

Start / End Page

  • 43 -

Electronic International Standard Serial Number (EISSN)

  • 1528-1167

International Standard Serial Number (ISSN)

  • 0013-9580

Digital Object Identifier (DOI)

  • 10.1111/j.1528-1167.2010.02829.x

Citation Source

  • Scopus