The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance.


Journal Article

Excessive deposition of fat in the liver (hepatic steatosis) is frequently accompanied by hepatic insulin resistance. Whether this correlation is due to a causal relationship between the conditions has been the subject of considerable debate, and the literature abounds with conflicting data and theories. Here we provide a perspective by defining the problem and its challenges, analyzing the possible causative relationships, and drawing some conclusions.

Full Text

Duke Authors

Cited Authors

  • Farese, RV; Zechner, R; Newgard, CB; Walther, TC

Published Date

  • May 2, 2012

Published In

Volume / Issue

  • 15 / 5

Start / End Page

  • 570 - 573

PubMed ID

  • 22560209

Pubmed Central ID

  • 22560209

Electronic International Standard Serial Number (EISSN)

  • 1932-7420

Digital Object Identifier (DOI)

  • 10.1016/j.cmet.2012.03.004


  • eng

Conference Location

  • United States