Principles of neural ensemble physiology underlying the operation of brain-machine interfaces.

Journal Article (Journal Article;Review)

Research on brain-machine interfaces has been ongoing for at least a decade. During this period, simultaneous recordings of the extracellular electrical activity of hundreds of individual neurons have been used for direct, real-time control of various artificial devices. Brain-machine interfaces have also added greatly to our knowledge of the fundamental physiological principles governing the operation of large neural ensembles. Further understanding of these principles is likely to have a key role in the future development of neuroprosthetics for restoring mobility in severely paralysed patients.

Full Text

Duke Authors

Cited Authors

  • Nicolelis, MAL; Lebedev, MA

Published Date

  • July 2009

Published In

Volume / Issue

  • 10 / 7

Start / End Page

  • 530 - 540

PubMed ID

  • 19543222

Electronic International Standard Serial Number (EISSN)

  • 1471-0048

Digital Object Identifier (DOI)

  • 10.1038/nrn2653


  • eng

Conference Location

  • England