Primate reaching cued by multichannel spatiotemporal cortical microstimulation.

Published

Journal Article

Both humans and animals can discriminate signals delivered to sensory areas of their brains using electrical microstimulation. This opens the possibility of creating an artificial sensory channel that could be implemented in neuroprosthetic devices. Although microstimulation delivered through multiple implanted electrodes could be beneficial for this purpose, appropriate microstimulation protocols have not been developed. Here, we report a series of experiments in which owl monkeys performed reaching movements guided by spatiotemporal patterns of cortical microstimulation delivered to primary somatosensory cortex through chronically implanted multielectrode arrays. The monkeys learned to discriminate microstimulation patterns, and their ability to learn new patterns and new behavioral rules improved during several months of testing. Significantly, information was conveyed to the brain through the interplay of microstimulation patterns delivered to multiple electrodes and the temporal order in which these electrodes were stimulated. This suggests multichannel microstimulation as a viable means of sensorizing neural prostheses.

Full Text

Duke Authors

Cited Authors

  • Fitzsimmons, NA; Drake, W; Hanson, TL; Lebedev, MA; Nicolelis, MAL

Published Date

  • May 23, 2007

Published In

Volume / Issue

  • 27 / 21

Start / End Page

  • 5593 - 5602

PubMed ID

  • 17522304

Pubmed Central ID

  • 17522304

Electronic International Standard Serial Number (EISSN)

  • 1529-2401

Digital Object Identifier (DOI)

  • 10.1523/JNEUROSCI.5297-06.2007

Language

  • eng

Conference Location

  • United States