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Brain-machine interfaces: past, present and future.

Publication ,  Journal Article
Lebedev, MA; Nicolelis, MAL
Published in: Trends Neurosci
September 2006

Since the original demonstration that electrical activity generated by ensembles of cortical neurons can be employed directly to control a robotic manipulator, research on brain-machine interfaces (BMIs) has experienced an impressive growth. Today BMIs designed for both experimental and clinical studies can translate raw neuronal signals into motor commands that reproduce arm reaching and hand grasping movements in artificial actuators. Clearly, these developments hold promise for the restoration of limb mobility in paralyzed subjects. However, as we review here, before this goal can be reached several bottlenecks have to be passed. These include designing a fully implantable biocompatible recording device, further developing real-time computational algorithms, introducing a method for providing the brain with sensory feedback from the actuators, and designing and building artificial prostheses that can be controlled directly by brain-derived signals. By reaching these milestones, future BMIs will be able to drive and control revolutionary prostheses that feel and act like the human arm.

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Published In

Trends Neurosci

DOI

ISSN

0166-2236

Publication Date

September 2006

Volume

29

Issue

9

Start / End Page

536 / 546

Location

England

Related Subject Headings

  • User-Computer Interface
  • Self-Help Devices
  • Prostheses and Implants
  • Neurology & Neurosurgery
  • Microelectrodes
  • Humans
  • Electroencephalography
  • Electrodes, Implanted
  • Computer Systems
  • Brain Diseases
 

Citation

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Lebedev, M. A., & Nicolelis, M. A. L. (2006). Brain-machine interfaces: past, present and future. Trends Neurosci, 29(9), 536–546. https://doi.org/10.1016/j.tins.2006.07.004
Lebedev, Mikhail A., and Miguel A. L. Nicolelis. “Brain-machine interfaces: past, present and future.Trends Neurosci 29, no. 9 (September 2006): 536–46. https://doi.org/10.1016/j.tins.2006.07.004.
Lebedev MA, Nicolelis MAL. Brain-machine interfaces: past, present and future. Trends Neurosci. 2006 Sep;29(9):536–46.
Lebedev, Mikhail A., and Miguel A. L. Nicolelis. “Brain-machine interfaces: past, present and future.Trends Neurosci, vol. 29, no. 9, Sept. 2006, pp. 536–46. Pubmed, doi:10.1016/j.tins.2006.07.004.
Lebedev MA, Nicolelis MAL. Brain-machine interfaces: past, present and future. Trends Neurosci. 2006 Sep;29(9):536–546.
Journal cover image

Published In

Trends Neurosci

DOI

ISSN

0166-2236

Publication Date

September 2006

Volume

29

Issue

9

Start / End Page

536 / 546

Location

England

Related Subject Headings

  • User-Computer Interface
  • Self-Help Devices
  • Prostheses and Implants
  • Neurology & Neurosurgery
  • Microelectrodes
  • Humans
  • Electroencephalography
  • Electrodes, Implanted
  • Computer Systems
  • Brain Diseases