Metaphors and the role of genes in development.
Journal Article (Journal Article)
In describing the flawless regularity of developmental processes and the correlation between changes at certain genetic loci and changes in morphology, biologists frequently employ two metaphors: that genes 'control' development, and that genomes embody 'programs' for development. Although these metaphors have an admirable sharpness and punch, they lead, when taken literally, to highly distorted pictures of developmental processes. A more balanced, and useful, view of the role of genes in development is that they act as suppliers of the material needs of development and, in some instances, as context-dependent catalysts of cellular changes, rather than as 'controllers' of developmental progress and direction. The consequences of adopting this alternative view of development are discussed.
Full Text
Duke Authors
Cited Authors
- Nijhout, HF
Published Date
- September 1990
Published In
Volume / Issue
- 12 / 9
Start / End Page
- 441 - 446
PubMed ID
- 1979486
Electronic International Standard Serial Number (EISSN)
- 1521-1878
International Standard Serial Number (ISSN)
- 0265-9247
Digital Object Identifier (DOI)
- 10.1002/bies.950120908
Language
- eng