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Microsatellite variation in populations of Drosophila pseudoobscura and Drosophila persimilis.

Publication ,  Journal Article
Noor, MA; Schug, MD; Aquadro, CF
Published in: Genetical research
February 2000

We have isolated, characterized and mapped 33 dinucleotide, three trinucleotide and one tetranucleotide repeat loci from the four major chromosomes of Drosophila pseudoobscura. Average inferred repeat unit length of the dinucleotide repeats is 12 repeat units, similar to D. melanogaster. Assays of D. pseudoobscura and populations of its sibling species, D. persimilis, using 10 of these loci show extremely high levels of variation compared with similar studies of dinucleotide repeat variation in D. melanogaster populations. The high levels of variation are consistent with an average mutation rate of approximately 10(-6) per locus per generation and an effective population size of D. pseudoobscura approximately four times larger than that of D. melanogaster. Consistent with allozymes and nucleotide sequence polymorphism, the dinucleotide repeat loci reveal minimal structure across four populations of D. pseudoobscura. Finally, our preliminary recombinational mapping of 24 of these microsatellites suggests that the total recombinational genome size may be larger than previously inferred using morphological mutant markers.

Duke Scholars

Published In

Genetical research

DOI

Publication Date

February 2000

Volume

75

Issue

1

Start / End Page

25 / 35

Related Subject Headings

  • Species Specificity
  • Microsatellite Repeats
  • Genetic Variation
  • Evolutionary Biology
  • Drosophila
  • DNA Primers
  • Base Sequence
  • Animals
  • 3105 Genetics
  • 0604 Genetics
 

Citation

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Noor, M. A., Schug, M. D., & Aquadro, C. F. (2000). Microsatellite variation in populations of Drosophila pseudoobscura and Drosophila persimilis. Genetical Research, 75(1), 25–35. https://doi.org/10.1017/s0016672399004024
Noor, M. A., M. D. Schug, and C. F. Aquadro. “Microsatellite variation in populations of Drosophila pseudoobscura and Drosophila persimilis.Genetical Research 75, no. 1 (February 2000): 25–35. https://doi.org/10.1017/s0016672399004024.
Noor MA, Schug MD, Aquadro CF. Microsatellite variation in populations of Drosophila pseudoobscura and Drosophila persimilis. Genetical research. 2000 Feb;75(1):25–35.
Noor, M. A., et al. “Microsatellite variation in populations of Drosophila pseudoobscura and Drosophila persimilis.Genetical Research, vol. 75, no. 1, Feb. 2000, pp. 25–35. Epmc, doi:10.1017/s0016672399004024.
Noor MA, Schug MD, Aquadro CF. Microsatellite variation in populations of Drosophila pseudoobscura and Drosophila persimilis. Genetical research. 2000 Feb;75(1):25–35.

Published In

Genetical research

DOI

Publication Date

February 2000

Volume

75

Issue

1

Start / End Page

25 / 35

Related Subject Headings

  • Species Specificity
  • Microsatellite Repeats
  • Genetic Variation
  • Evolutionary Biology
  • Drosophila
  • DNA Primers
  • Base Sequence
  • Animals
  • 3105 Genetics
  • 0604 Genetics