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Therapeutic goals in patients with refractory chronic angina.

Publication ,  Journal Article
Cohen, MG; Pascual, M; Scirica, BM; Magnus Ohman, E
Published in: Rev Esp Cardiol
May 2010

Refractory angina presents a major clinical challenge for everyday medical practice. Despite the widespread use of statins and improvements in revascularization techniques, a substantial proportion of patients with preserved left ventricular function and no life-threatening arrhythmias remain symptomatic, with severe debilitating angina. Because the rate of major cardiac events in this population is relatively low, the major aim of therapy should be not only to prolong survival but also to improve quality of life. The cornerstone of therapy for all these patients should be the aggressive modification of risk factors using evidence-based treatment, with the aim of stabilizing the disease process and improving overall survival. No opportunity for revascularization should be overlooked. Complementary approaches should be implemented to raise the angina threshold by either reducing oxygen demand or improving hemodynamics to increase myocardial oxygen supply. This review provides an update on therapeutic techniques and goals, and reinforces the need for a multidisciplinary approach to the management of patients with refractory angina.

Duke Scholars

Published In

Rev Esp Cardiol

DOI

EISSN

1579-2242

Publication Date

May 2010

Volume

63

Issue

5

Start / End Page

571 / 582

Location

Spain

Related Subject Headings

  • Terminology as Topic
  • Risk Factors
  • Quality of Life
  • Myocardial Revascularization
  • Humans
  • Goals
  • Evidence-Based Medicine
  • Drug Resistance
  • Chronic Disease
  • Cardiovascular System & Hematology
 

Citation

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Cohen, M. G., Pascual, M., Scirica, B. M., & Magnus Ohman, E. (2010). Therapeutic goals in patients with refractory chronic angina. Rev Esp Cardiol, 63(5), 571–582. https://doi.org/10.1016/s1885-5857(10)70119-5
Cohen, Mauricio G., Mario Pascual, Benjamin M. Scirica, and E. Magnus Ohman. “Therapeutic goals in patients with refractory chronic angina.Rev Esp Cardiol 63, no. 5 (May 2010): 571–82. https://doi.org/10.1016/s1885-5857(10)70119-5.
Cohen MG, Pascual M, Scirica BM, Magnus Ohman E. Therapeutic goals in patients with refractory chronic angina. Rev Esp Cardiol. 2010 May;63(5):571–82.
Cohen, Mauricio G., et al. “Therapeutic goals in patients with refractory chronic angina.Rev Esp Cardiol, vol. 63, no. 5, May 2010, pp. 571–82. Pubmed, doi:10.1016/s1885-5857(10)70119-5.
Cohen MG, Pascual M, Scirica BM, Magnus Ohman E. Therapeutic goals in patients with refractory chronic angina. Rev Esp Cardiol. 2010 May;63(5):571–582.

Published In

Rev Esp Cardiol

DOI

EISSN

1579-2242

Publication Date

May 2010

Volume

63

Issue

5

Start / End Page

571 / 582

Location

Spain

Related Subject Headings

  • Terminology as Topic
  • Risk Factors
  • Quality of Life
  • Myocardial Revascularization
  • Humans
  • Goals
  • Evidence-Based Medicine
  • Drug Resistance
  • Chronic Disease
  • Cardiovascular System & Hematology