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The contrast media iohexol causes vasoconstriction of the proximal left anterior descending coronary artery: implications for appropriate stent sizing.

Publication ,  Journal Article
Kelly, RV; Gillespie, MJ; Cohen, MG; McLaughlin, DP; Magnus Ohman, E; Stouffer, GA
Published in: Angiology
2008

The effect of the contrast agent iohexol on reference vessel size in patients with proximal left anterior descending disease is unknown. Quantitative coronary angiography and intravascular ultrasound were performed in 15 patients with atherosclerotic disease of the proximal left anterior descending. Mean proximal reference vessel diameter was 2.95 +/- 0.59 mm with quantitative coronary angiography and 4.65 +/- 0.66 mm with intravascular ultrasound (P < .05). Intracoronary injection of iohexol resulted in a significant decrease in intravascular ultrasound-measured proximal reference vessel diameter from 4.65 +/- 0.66 mm to 4.47 +/- 0.68 mm (P = .002). Vasoconstrictive response to iohexol in the proximal reference vessel ranged from -0.04 mm to 0.5 mm with a mean of 0.18 +/- 0.16 mm. This study shows that iohexol can cause significant vasoconstriction of the proximal reference vessel in patients with severe disease involving the proximal left anterior descending.

Duke Scholars

Published In

Angiology

DOI

EISSN

1940-1574

Publication Date

2008

Volume

59

Issue

5

Start / End Page

574 / 580

Location

United States

Related Subject Headings

  • Vasoconstriction
  • Ultrasonography
  • Stents
  • Prosthesis Fitting
  • Middle Aged
  • Male
  • Iohexol
  • Injections
  • Humans
  • Female
 

Citation

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Kelly, R. V., Gillespie, M. J., Cohen, M. G., McLaughlin, D. P., Magnus Ohman, E., & Stouffer, G. A. (2008). The contrast media iohexol causes vasoconstriction of the proximal left anterior descending coronary artery: implications for appropriate stent sizing. Angiology, 59(5), 574–580. https://doi.org/10.1177/0003319708318375
Kelly, Robert V., Michael J. Gillespie, Mauricio G. Cohen, David P. McLaughlin, E. Magnus Ohman, and George A. Stouffer. “The contrast media iohexol causes vasoconstriction of the proximal left anterior descending coronary artery: implications for appropriate stent sizing.Angiology 59, no. 5 (2008): 574–80. https://doi.org/10.1177/0003319708318375.
Kelly RV, Gillespie MJ, Cohen MG, McLaughlin DP, Magnus Ohman E, Stouffer GA. The contrast media iohexol causes vasoconstriction of the proximal left anterior descending coronary artery: implications for appropriate stent sizing. Angiology. 2008;59(5):574–80.
Kelly, Robert V., et al. “The contrast media iohexol causes vasoconstriction of the proximal left anterior descending coronary artery: implications for appropriate stent sizing.Angiology, vol. 59, no. 5, 2008, pp. 574–80. Pubmed, doi:10.1177/0003319708318375.
Kelly RV, Gillespie MJ, Cohen MG, McLaughlin DP, Magnus Ohman E, Stouffer GA. The contrast media iohexol causes vasoconstriction of the proximal left anterior descending coronary artery: implications for appropriate stent sizing. Angiology. 2008;59(5):574–580.
Journal cover image

Published In

Angiology

DOI

EISSN

1940-1574

Publication Date

2008

Volume

59

Issue

5

Start / End Page

574 / 580

Location

United States

Related Subject Headings

  • Vasoconstriction
  • Ultrasonography
  • Stents
  • Prosthesis Fitting
  • Middle Aged
  • Male
  • Iohexol
  • Injections
  • Humans
  • Female