The pharmacology of methotrexate.
Publication
, Journal Article
Olsen, EA
Published in: J Am Acad Dermatol
August 1991
Methotrexate is a useful antimetabolite for the treatment of both benign and malignant proliferative disorders. When the pharmacokinetics and potential toxicity of this drug are understood, treatment regimens can be tailored to the underlying kinetics of the target population. With the appropriate knowledge of the importance of urinary excretion of methotrexate and factors that influence this and with the ready availability of leucovorin, toxicity can be avoided in all but the most unusual of circumstances.
Duke Scholars
Published In
J Am Acad Dermatol
DOI
ISSN
0190-9622
Publication Date
August 1991
Volume
25
Issue
2 Pt 1
Start / End Page
306 / 318
Location
United States
Related Subject Headings
- Skin
- Methotrexate
- Lung
- Leucovorin
- Kidney
- Humans
- Drug Therapy, Combination
- Digestive System
- Dermatology & Venereal Diseases
- Central Nervous System
Citation
APA
Chicago
ICMJE
MLA
NLM
Olsen, E. A. (1991). The pharmacology of methotrexate. J Am Acad Dermatol, 25(2 Pt 1), 306–318. https://doi.org/10.1016/0190-9622(91)70199-c
Olsen, E. A. “The pharmacology of methotrexate.” J Am Acad Dermatol 25, no. 2 Pt 1 (August 1991): 306–18. https://doi.org/10.1016/0190-9622(91)70199-c.
Olsen EA. The pharmacology of methotrexate. J Am Acad Dermatol. 1991 Aug;25(2 Pt 1):306–18.
Olsen, E. A. “The pharmacology of methotrexate.” J Am Acad Dermatol, vol. 25, no. 2 Pt 1, Aug. 1991, pp. 306–18. Pubmed, doi:10.1016/0190-9622(91)70199-c.
Olsen EA. The pharmacology of methotrexate. J Am Acad Dermatol. 1991 Aug;25(2 Pt 1):306–318.
Published In
J Am Acad Dermatol
DOI
ISSN
0190-9622
Publication Date
August 1991
Volume
25
Issue
2 Pt 1
Start / End Page
306 / 318
Location
United States
Related Subject Headings
- Skin
- Methotrexate
- Lung
- Leucovorin
- Kidney
- Humans
- Drug Therapy, Combination
- Digestive System
- Dermatology & Venereal Diseases
- Central Nervous System