Acquired thrombotic risk factors in the critical care setting.
Journal Article (Journal Article;Review)
Acquired thrombotic risk factors include a variety of noninherited clinical conditions that can predispose an individual to an increased risk for venous thromboembolism. For patients in a critical care setting, certain acquired risk factors represent chronic conditions that the patients may have had before the current acute illness (e.g., malignancy, various cardiovascular risk factors, certain medications), whereas others may be directly related to the reason the patient is in an intensive care unit or the patient's management there (e.g., postoperative state, trauma, indwelling vascular access, certain medications). Optimal thromboprophylactic strategies depend on individual patient risk profiles including an assessment of the specific clinical setting. Treatment for patients with acquired thrombotic risk factors includes anticoagulant therapy and, if possible, resolution of the acquired risk factor(s). Heparin-induced thrombocytopenia represents a unique clinical situation in which all sources of heparin must be discontinued and the patient started on an alternative anticoagulant (e.g., a direct thrombin inhibitor) in the acute setting. The duration of anticoagulant therapy would vary depending on the specific clinical setting.
Full Text
Duke Authors
Cited Authors
- Ortel, TL
Published Date
- February 2010
Published In
Volume / Issue
- 38 / 2 Suppl
Start / End Page
- S43 - S50
PubMed ID
- 20083913
Electronic International Standard Serial Number (EISSN)
- 1530-0293
Digital Object Identifier (DOI)
- 10.1097/CCM.0b013e3181c9ccc8
Language
- eng
Conference Location
- United States