Lung transplantation in the older patient


Journal Article (Review)

PURPOSE OF REVIEW: Lung transplantation remains controversial in older patients. This review will critically evaluate the current literature on the practice and outcomes in older lung transplantation recipients. RECENT FINDINGS: International Society of Heart and Lung Transplant guidelines recommended upper age limits for lung transplantation. Increasing numbers of transplant centers, however, are offering lung transplantation to older patients up to and exceeding these guidelines. In fact, patients over 65 years represent the fastest growing group of lung transplantation recipients in recent years. Current literature documents that acceptable short- and medium-term outcomes can be achieved in the older lung transplantation recipient although there are unique considerations in this age cohort including infections and renal dysfunction. In contrast to earlier reports, recent studies suggest that bilateral transplantation is an effective therapy in older patients with endstage lung disease. SUMMARY: Outcomes in the older lung transplantation recipients are acceptable. In this population, however, there are special considerations in the pretransplant, perioperative and posttransplant phases. Importantly, current allocation systems allow for, and can even favor, older lung transplantation recipients, suggesting the number of lung transplantation in older recipients is likely to continue to increase. © 2007 Lippincott Williams & Wilkins, Inc.

Full Text

Duke Authors

Cited Authors

  • Snyder, LD; Musselwhite, LW; Palmer, SM

Published Date

  • October 1, 2007

Published In

Volume / Issue

  • 12 / 5

Start / End Page

  • 485 - 490

Electronic International Standard Serial Number (EISSN)

  • 1531-7013

International Standard Serial Number (ISSN)

  • 1087-2418

Digital Object Identifier (DOI)

  • 10.1097/MOT.0b013e32828d8b7c

Citation Source

  • Scopus