Pre-treatment with somatostatin in the anaesthetic management of a patient with carcinoid syndrome.
Journal Article (Journal Article)
Carcinoid syndrome produces flushing, bronchoconstriction and gastrointestinal hypermotility secondary to serotonin, histamine, bradykinin and prostaglandin release. A variety of drugs, foods and anaesthetic agents may provoke this syndrome. Under anaesthesia, the flushing produced may be associated with acute hypotension and cardiovascular collapse; this phenomenon is called a carcinoid crisis. Recently, somatostatin analogue has been used successfully to treat intraoperative carcinoid crisis. In this report, we present a 66-year-old lady with carcinoid syndrome who was pre-treated with 50 micrograms somatostatin analogue IV and IM prior to surgical manipulation. The anaesthetic course was relatively uneventful and the patient did well postoperatively.
Full Text
Duke Authors
Cited Authors
- Parris, WC; Oates, JA; Kambam, J; Shmerling, R; Sawyers, JF
Published Date
- July 1988
Published In
Volume / Issue
- 35 / 4
Start / End Page
- 413 - 416
PubMed ID
- 2900085
International Standard Serial Number (ISSN)
- 0832-610X
Digital Object Identifier (DOI)
- 10.1007/BF03010865
Language
- eng
Conference Location
- United States