Pre-treatment with somatostatin in the anaesthetic management of a patient with carcinoid syndrome.
Journal Article (Journal Article)
Carcinoid syndrome produces flushing, bronchoconstriction and gastrointestinal hypermotility secondary to serotonin, histamine, bradykinin and prostaglandin release. A variety of drugs, foods and anaesthetic agents may provoke this syndrome. Under anaesthesia, the flushing produced may be associated with acute hypotension and cardiovascular collapse; this phenomenon is called a carcinoid crisis. Recently, somatostatin analogue has been used successfully to treat intraoperative carcinoid crisis. In this report, we present a 66-year-old lady with carcinoid syndrome who was pre-treated with 50 micrograms somatostatin analogue IV and IM prior to surgical manipulation. The anaesthetic course was relatively uneventful and the patient did well postoperatively.
- Parris, WC; Oates, JA; Kambam, J; Shmerling, R; Sawyers, JF
- July 1988
Volume / Issue
- 35 / 4
Start / End Page
- 413 - 416
International Standard Serial Number (ISSN)
Digital Object Identifier (DOI)
- United States