Pre-treatment with somatostatin in the anaesthetic management of a patient with carcinoid syndrome.

Journal Article (Journal Article)

Carcinoid syndrome produces flushing, bronchoconstriction and gastrointestinal hypermotility secondary to serotonin, histamine, bradykinin and prostaglandin release. A variety of drugs, foods and anaesthetic agents may provoke this syndrome. Under anaesthesia, the flushing produced may be associated with acute hypotension and cardiovascular collapse; this phenomenon is called a carcinoid crisis. Recently, somatostatin analogue has been used successfully to treat intraoperative carcinoid crisis. In this report, we present a 66-year-old lady with carcinoid syndrome who was pre-treated with 50 micrograms somatostatin analogue IV and IM prior to surgical manipulation. The anaesthetic course was relatively uneventful and the patient did well postoperatively.

Full Text

Duke Authors

Cited Authors

  • Parris, WC; Oates, JA; Kambam, J; Shmerling, R; Sawyers, JF

Published Date

  • July 1988

Published In

Volume / Issue

  • 35 / 4

Start / End Page

  • 413 - 416

PubMed ID

  • 2900085

International Standard Serial Number (ISSN)

  • 0832-610X

Digital Object Identifier (DOI)

  • 10.1007/BF03010865


  • eng

Conference Location

  • United States