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Noninvasive tools to assess liver disease.

Publication ,  Journal Article
Clark, PJ; Patel, K
Published in: Curr Opin Gastroenterol
May 2011

PURPOSE OF REVIEW: To improve understanding of recent developments in the noninvasive assessment of fibrosis and their potential clinical application to a range of chronic liver diseases. RECENT FINDINGS: Many noninvasive tests have evolved from their primary validation in chronic hepatitis C virus (HCV) infection to integration into clinical management algorithms for chronic liver disease of varying cause. Recent studies consider the use of these techniques in sequence or in combination, and compare the performance of serum and imaging-based noninvasive techniques to identify patients with significant fibrosis, or those at most risk of clinical sequelae from advanced-stage disease. Methods developed in chronic hepatitis C have now been applied in different chronic liver diseases, including nonalcoholic fatty liver disease, alcoholic liver disease, HIV/HCV co-infection and primary biliary cirrhosis. A number of new management algorithms have been developed to facilitate the integration of noninvasive techniques into clinical practice. SUMMARY: Noninvasive tools to assess liver diseases continue to evolve. New imaging technologies have been developed. Existing biomarkers and imaging modalities have been better integrated into clinical practice algorithms, and applied to different chronic liver diseases. Noninvasive techniques will likely continue to be refined and play an important role in the future management of patients with chronic liver disease.

Duke Scholars

Published In

Curr Opin Gastroenterol

DOI

EISSN

1531-7056

Publication Date

May 2011

Volume

27

Issue

3

Start / End Page

210 / 216

Location

United States

Related Subject Headings

  • Prognosis
  • Liver Diseases
  • Humans
  • Gastroenterology & Hepatology
  • Elasticity Imaging Techniques
  • Chronic Disease
  • Biomarkers
  • Algorithms
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Clark, P. J., & Patel, K. (2011). Noninvasive tools to assess liver disease. Curr Opin Gastroenterol, 27(3), 210–216. https://doi.org/10.1097/MOG.0b013e328343e9a3
Clark, Paul J., and Keyur Patel. “Noninvasive tools to assess liver disease.Curr Opin Gastroenterol 27, no. 3 (May 2011): 210–16. https://doi.org/10.1097/MOG.0b013e328343e9a3.
Clark PJ, Patel K. Noninvasive tools to assess liver disease. Curr Opin Gastroenterol. 2011 May;27(3):210–6.
Clark, Paul J., and Keyur Patel. “Noninvasive tools to assess liver disease.Curr Opin Gastroenterol, vol. 27, no. 3, May 2011, pp. 210–16. Pubmed, doi:10.1097/MOG.0b013e328343e9a3.
Clark PJ, Patel K. Noninvasive tools to assess liver disease. Curr Opin Gastroenterol. 2011 May;27(3):210–216.

Published In

Curr Opin Gastroenterol

DOI

EISSN

1531-7056

Publication Date

May 2011

Volume

27

Issue

3

Start / End Page

210 / 216

Location

United States

Related Subject Headings

  • Prognosis
  • Liver Diseases
  • Humans
  • Gastroenterology & Hepatology
  • Elasticity Imaging Techniques
  • Chronic Disease
  • Biomarkers
  • Algorithms
  • 3202 Clinical sciences
  • 1103 Clinical Sciences