Quinone oxidoreductase (NQO1) gene polymorphism may not confer a susceptibility to mood disorders.


Journal Article

Quinone oxidoreductase (NQO1) plays a key role in the cellular antioxidant defense by detoxifying quinine derivatives. Case-control association study of the possible relationship between the NQO1 gene polymorphism and mood disorders (patients with major depressive disorder, n=61; patients with bipolar I disorder, n=80; control, n=106) was carried out using PCR-based techniques. These preliminary results showed that the NQO1 gene polymorphism was not related to a susceptibility to mood disorders.

Full Text

Duke Authors

Cited Authors

  • Pae, C-U; Yoon, S-J; Patkar, AA; Kim, J-J; Lee, C; Paik, I-H

Published Date

  • September 30, 2007

Published In

Volume / Issue

  • 153 / 1

Start / End Page

  • 83 - 86

PubMed ID

  • 17644186

Pubmed Central ID

  • 17644186

International Standard Serial Number (ISSN)

  • 0165-1781

Digital Object Identifier (DOI)

  • 10.1016/j.psychres.2006.01.011


  • eng

Conference Location

  • Ireland