Clinical variables associated with early administration of antipsychotics in bipolar mania.


Journal Article

This study evaluated the clinical variables associated with the early administration of antipsychotics for the treatment of bipolar mania. 63 out of 97 inpatients with bipolar I disorder according to the DSM-IV criteria and who were consecutively admitted to the Kangnam St. Mary's Hospital, between September 2002 and March 2004, were included in the study. Regression analysis was run on the clinical variables in order to identify the factors affecting the early administration of antipsychotics. The route of admission and exposure to antipsychotics at the last follow-up were found to be associated with the early administration of antipsychotics (odds ratios=33.0 and 13.1, respectively). This study suggests that some clinical factors in bipolar mania might be linked to the earlier antipsychotic treatment. However, more studies will be needed to confirm this finding.

Full Text

Duke Authors

Cited Authors

  • Pae, C-U; Kim, T-S; Lee, K-U; Kim, J-J; Patkar, AA; Masand, PS; Ghaemi, SN; Lee, C-U; Lee, S-J; Lee, C; Paik, I-H

Published Date

  • January 2006

Published In

Volume / Issue

  • 30 / 1

Start / End Page

  • 151 - 154

PubMed ID

  • 16253411

Pubmed Central ID

  • 16253411

International Standard Serial Number (ISSN)

  • 0278-5846

Digital Object Identifier (DOI)

  • 10.1016/j.pnpbp.2005.08.024


  • eng

Conference Location

  • England