Twenty-first century tobacco use: it is not just a risk factor anymore.


Journal Article (Review)

Despite availability of effective treatments for nicotine addiction, smoking remains prevalent with serious health consequences. Most smokers recognize the ill effects of smoking but are unable to quit. Nicotine addiction may be viewed as any other chronic illness that results from exposure to a recognizable agent (tobacco) and manifests with a well-documented set of signs and symptoms. Much like any chronic disease, both environmental and genetic factors determine the occurrence and severity of this affliction. There has been recent focus on uncovering the genetic basis of nicotine addiction. In this article, we have attempted to briefly review the current evidence for the role of genetics in smoking as well as comment on available pharmacotherapeutic options for treating nicotine dependence.

Full Text

Cited Authors

  • Khurana, S; Batra, V; Patkar, AA; Leone, FT

Published Date

  • April 2003

Published In

Volume / Issue

  • 97 / 4

Start / End Page

  • 295 - 301

PubMed ID

  • 12693789

Pubmed Central ID

  • 12693789

International Standard Serial Number (ISSN)

  • 0954-6111

Digital Object Identifier (DOI)

  • 10.1053/rmed.2002.1443


  • eng

Conference Location

  • England