Serum bupropion levels in 2 breastfeeding mother-infant pairs.


Journal Article

BACKGROUND:These are the first reported data on bupropion and hydroxybupropion levels in infants whose treated mothers were breastfeeding. The information will assist physicians and parents in the risk-benefit decision-making process for bupropion treatment during breastfeeding. METHOD:Serum samples were obtained by venipuncture from 2 mother-infant pairs. The serum was assayed for levels of bupropion and its most active metabolite, hydroxybupropion. RESULTS:Neither infant had quantifiable serum levels of bupropion or its metabolite at steady state. Neither infant had medical problems during the time of maternal therapy. CONCLUSION:We recommend obtaining and publishing additional serum level findings for breastfeeding mother-infant pairs since data for bupropion are favorable but limited.

Full Text

Cited Authors

  • Baab, SW; Peindl, KS; Piontek, CM; Wisner, KL

Published Date

  • October 2002

Published In

Volume / Issue

  • 63 / 10

Start / End Page

  • 910 - 911

PubMed ID

  • 12416600

Pubmed Central ID

  • 12416600

Electronic International Standard Serial Number (EISSN)

  • 1555-2101

International Standard Serial Number (ISSN)

  • 0160-6689

Digital Object Identifier (DOI)

  • 10.4088/jcp.v63n1008


  • eng