Risk factors and outcomes of pancreatitis after open heart surgery.

Published

Journal Article

BACKGROUND: We sought to analyze the risk factors and natural history associated with post-cardiac surgery acute pancreatitis. METHODS: Retrospective analysis of all patients having undergone cardiac surgery at our hospital between January 1, 1992, and October 1, 2001. RESULTS: A total of 10,249 cardiac operations were performed. Thirty-nine (0.4%) patients developed postoperative pancreatitis. There was a higher incidence during the period spanning 1992 through 1996 than 1997 through 2001 (0.6% versus 0.2%, P< .05). Patients with pancreatitis had longer postoperative length of stay (51+/-5 days versus 10+/-1 days, P<.05) and a greater in-hospital mortality rate (28% versus 4%, P<.05) than patients who did not develop pancreatitis. A history of alcohol abuse, cardiac surgery performed during 1992 to 1996, increased cardiopulmonary bypass time, and increased cross-clamp time were independent risk factors for the development of pancreatitis. Multiple-organ failure was an independent predictor for death among patients with pancreatitis. CONCLUSIONS: Although the frequency of post-cardiac surgery pancreatitis is diminishing, it is still associated with significant mortality.

Full Text

Cited Authors

  • Perez, A; Ito, H; Farivar, RS; Cohn, LH; Byrne, JG; Rawn, JD; Aranki, SF; Zinner, MJ; Tilney, NL; Brooks, DC; Ashley, SW; Banks, PA; Whang, EE

Published Date

  • September 2005

Published In

Volume / Issue

  • 190 / 3

Start / End Page

  • 401 - 405

PubMed ID

  • 16105526

Pubmed Central ID

  • 16105526

International Standard Serial Number (ISSN)

  • 0002-9610

Digital Object Identifier (DOI)

  • 10.1016/j.amjsurg.2005.03.004

Language

  • eng

Conference Location

  • United States