Cryptococcosis in solid organ transplant recipients: current state of the science.

Journal Article (Journal Article;Review)

Cryptococcosis remains a significant opportunistic infection in solid organ transplant recipients. Disease presentation and outcomes may be affected by, among other factors, the use of calcineurin inhibitor immunosuppressive agents. It is being increasingly recognized that rapid reversal of immunosuppression in transplant recipients treated for cryptococcosis incurs the risk of immune reconstitution inflammatory syndrome, which resembles worsening disease or relapse. This review summarizes the current state of knowledge regarding cryptococcosis in transplant recipients and highlights areas where future investigations are needed to further optimize outcomes for these patients.

Full Text

Duke Authors

Cited Authors

  • Singh, N; Dromer, F; Perfect, JR; Lortholary, O

Published Date

  • November 15, 2008

Published In

Volume / Issue

  • 47 / 10

Start / End Page

  • 1321 - 1327

PubMed ID

  • 18840080

Pubmed Central ID

  • 18840080

Electronic International Standard Serial Number (EISSN)

  • 1537-6591

Digital Object Identifier (DOI)

  • 10.1086/592690


  • eng

Conference Location

  • United States