In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important molds.


Journal Article

The in vitro activity of the new antifungal drug pneumocandin L-743,872 against 55 isolates of clinically important molds was examined by an adapted macrobroth dilution method for yeasts. Pneumocandin L-743,872 exhibited in vitro antifungal activity against Alternaria sp., Aspergillus flavus, Aspergillus fumigatus, Curvularia lunata, Exophiala jeanselmei, Fonsecaea pedrosoi, Paecilomyces variotii, and Scedosporium apiospermum. The drug appeared to lack significant in vitro inhibitory activity against Fusarium oxysporum, Fusarium solani, Rhizopus arrhizus, Paecilomyces lilacinus, and Scedosporium prolificans.

Full Text

Duke Authors

Cited Authors

  • Del Poeta, M; Schell, WA; Perfect, JR

Published Date

  • August 1997

Published In

Volume / Issue

  • 41 / 8

Start / End Page

  • 1835 - 1836

PubMed ID

  • 9257774

Pubmed Central ID

  • 9257774

International Standard Serial Number (ISSN)

  • 0066-4804


  • eng

Conference Location

  • United States